1. How to submit my research paper? What’s the process of publication of my paper?
The journal receives submitted manuscripts via email only. Please submit your research paper in .doc or.pdf format to the submission email: ijlbpr@ejournal.net.
You’ll be given a paper number if your submission is successful. Your paper then will undergo peer review process, which may take approximately one and a half months under normal circumstances, three tops.
After blind peer review, you will receive the notification letter with the review result of your paper...
2. Can I submit an abstract?
The journal publishes full research papers. So only full paper submission should be [Read More]

Effectiveness in the Treatment of Iron Deficiency Anemia in Sprague-Dawley Rats Using Freeze- Dried Crocodile Blood

Win Chaeychomsri1, Ekawit Threenet2, Sudawan Chaeychomsri2, and Jindawan Siruntawineti 2
1 Department of Zoology, Faculty of Science, Kasetsart University, Bangkok 10900, Thailand
2 Graduate School, Kasetsart University, Bangkok 10900, Thailand
Central Laboratory and Greenhouse Complex, Faculty of Agriculture at Kamphaeng Saen, Kasetsart University, Kamphaeng Saen, Nakhon Pathom 73140, Thailand
Abstract—The effectiveness of the treatment of Iron Deficiency Anemia (IDA) in rats using Freeze-dried Crocodile Blood (FCB) was performed by using 10 groups of 5, male, Sprague-Dawley rats. After 4 weeks of IDA induction (groups G2-G10), the rat’s tail-vein blood was collected for hematological and serum protein investigations. The induced groups hemoglobin (5.59±0.25 g/dl) and hematocrit (26.46±6.45%) were significantly different (p<0.05) from the control group (G1). Rats (G2-G8) were treated with FCB in various doses as design for 24 weeks. Group G6 fed FCB 500 mg and vitamin C 50 mg was as effective as groups G4-G5, showed hemoglobin (12.20±0.82 gm/dl) and hematocrit (33.06±2.09%) significantly different (p<0.05) from groups G2-G3. These revealed that the FCB and low dose of vitamin C was efficient when used to increase hemoglobin and hematocrit values. After treatments, the FCB groups had no detrimental effect on internal organs - with the exception of group G10 fed with AIN93G-Fe diet and 60 mg ferrous sulfate per day. The serum protein analysis demonstrated an alpha-1 proteinase inhibitor (alpha-1-inhibitor III) was released in high volume; depend on FCB treatment dose. Furthermore, haptoglobin and preprohapto-globin from the IDA rats were released in higher volumes than G1 or FCB groups.

Index Terms—Iron deficiency anemia, Crocodile blood, Alpha-1 protease inhibitor, Haptoglobin, Preprohaptoglobin

Cite: Win Chaeychomsri, Ekawit Threenet, Sudawan Chaeychomsri, and Jindawan Siruntawineti, "Effectiveness in the Treatment of Iron Deficiency Anemia in Sprague-Dawley Rats Using Freeze- Dried Crocodile Blood," International Journal of Life Sciences Biotechnology and Pharma Research, Vol. 4, No. 1, pp. 42-49, January 2015.
Copyright © 2012-2015 International Journal of Life Sciences Biotechnology and Pharma Research, All Rights Reserved