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Effect of Coleus Forskohlii Root Extracts on Liver Marker Enzymes

Malarvizhi A1 and Sivagami Srinivasan2
1.Department of Biochemistry, D.G. Govt. Arts College for women, Mayiladuthurai, Tamil Nadu, India
2.Department of Biochemistry, Biotechnology and Bioinformatics, Avinashilingam Institute for Home Science and Higher Education for Women, Coimbatore, Tamil Nadu, India
Abstract—The roots of Coleus forskohlii were shade dried and powdered. The powder was extracted with different solvents such as petroleum ether, chloroform, acetone and methanol. The Balb/C mice weighing between 25-30g were induced with DLA cells and treated with the extracts of Coleus forskohlii roots to evaluate the activity of the liver marker enzymes. The liver marker enzymes such as alkaline phosphatase, acid phosphatase, aspartate transaminase, alanine transaminase, lactate dehydrogenase were found to have increased in the serum, indicating the liver damage and were reduced significantly in the methanol extract treated mice.

Index TermsColeus forskohlii, liver marker enzymes, alkaline phosphatase, acid phosphatase, aspartate transaminase, alanine transaminase, lactate dehydrogenase

Cite:Malarvizhi A and Sivagami Srinivasan, "Effect of Coleus Forskohlii Root Extracts on Liver Marker Enzymes," International Journal of Life Sciences Biotechnology and Pharma Research, Vol. 4, No. 3, pp. 158-162, July 2015.

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