Abstract Issue

Volume 14 Issue 5 (May) 2025

Original Articles

Role of Vitamin A in Measles complications: A study in Garhwal region of Uttarakhand
Tanvi, Ayesha Imran, Ankita Giri

Background: Measles is a highly communicable viral infection with serious complications.There have been continued outbreak of measles in countries and it has more than 90% of secondary attack rate.It has been observed that Vitamin A deficiency is a recognised risk factor for severe measles infection.Therefore we conducted this study to see association between measles and Vitamin A. Objective: Measurement of vitamin A level in measles patient and to find out its association with measles. Methods: This is a prospective descriptive study.Children presented to pediatric OPD/IPD with high grade fever and rash typical of measles that started behind ear enrolled in study. Result: A total of 109 IgM positivemeasles, 34 patients were admitted with complications of measles which accounted for 31.19% of total confirmed cases of measles and 9.9 % of clinical measles.Vitamin A levels in children with measles ranged from 0.01-0.23 mg/L; 30 (88.2%) were low. In line with the hypothesis of this study, children with complicated measles are associated with lower levels of vitamin A levels. Conclusion: In our study Vitamin A levels in children with measles ranged from 0.01-0.23 mg/L; 30 (88.2%) were low. This was in line with the hypothesis of this study; children with complicated measles are associated with lower levels of vitamin A levels.It was seen that children with low levels were more likely -to have a fever at a temperature of 40°C or higher (78% vs 41%), to have a fever for 7 days or more (51% vs 25%), to get hospitalized (56% vs 32%).

 
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