Background: Induction of anesthesia and endotracheal intubation are known to provoke significant haemodynamic changes due to the physiological stress response and the pharmacologic effects of anesthetic agents. Achieving cardiovascular stability during this period is a key goal in anesthetic management. Propofol and Sevoflurane are widely used agents, each with unique advantages and potential side effects. Co-induction with both agents may offer a synergistic effect, reducing individual drug dosages and improving haemodynamic outcomes. Objective: This observational study aims to assess the haemodynamic responses—specifically changes in heart rate and blood pressure—during the induction and intubation phases in patients co-induced with Propofol and Sevoflurane. Methods: The study was conducted on a selected group of patients undergoing elective surgeries under general anesthesia. Baseline haemodynamic parameters were recorded and monitored at various time intervals throughout the induction and intubation process. The focus was on evaluating fluctuations and trends in systolic, diastolic, and mean arterial pressures, along with heart rate. Results: The findings suggest that co-induction with Sevoflurane and Propofol leads to better haemodynamic stability, with minimal fluctuations observed during both induction and intubation. The combination appeared to attenuate the typical sympathetic response commonly associated with laryngoscopy and intubation. Conclusion: Co-induction using Sevoflurane and Propofol is a clinically effective strategy to achieve smooth induction while maintaining haemodynamic stability. These results support the integration of this approach in routine anesthetic practice, especially in patients where cardiovascular fluctuations pose a significant risk.