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Volume 13 Issue 4 (April) 2024

Original Articles

Comparison Of Umbilical Cord Blood Bilirubin And Bilirubin Albumin Ratio In Predicting Neonatal Hyperbilirubinemia
Dr. Radhika Mantry, Dr. Sohini Ghosh, Dr. Alka Agrawal

Introduction: In newborns, hyperbilirubinemia is a common medical issue. When bilirubin levels rise to unusually high levels and cause neurological issues, it becomes troublesome. The aim of present study is to compare the umbilical cord blood bilirubin and bilirubin albumin ratio in predicting neonatal hyperbilirubinemia. Material & methods: The prospective observational study was conducted at NICU and post natal wards for a period of 1 year. Until five days or until they were discharged, babies were checked every day for signs of jaundice. If clinical icterus was detected within 72 hours of delivery or at any point following, according to Kramer's guideline, venous blood was sent for bilirubin measurement. The p-value<0.05 was considered statistically significant. Results: Out of 100 patients 25% had hyperbilirubinemia. Male patients (55%) were more as compared to females (45%). Most common mode of delivery was vaginal (69%). 77% had birth weight 2.5-3.5kg. Correlation of UCB cut-off of 2 mg/dL and UCB cut-off of 2.5 mg/dL to predict neonatal hyperbilirubinemia were both highly statistically significant with p-value of <0.001. Statistically significant correlation between the BAR and neonatal hyperbilirubinemia with a p-value <0.001 with both BAR cut-offs of 0.59 and 0.69. UCB cut-off of 2 mg/dL had a better sensitivity and UCB 2.5 mg/dL had a better specificity. BAR 0.59 has a better sensitivity and BAR 0.69 has a better specificity. Conclusion: Neonatal hyperbilirubinemia can be predicted well by both UCB and BAR, However UCB is a stronger predictor than BAR.

 
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