Aim: To see and compare tramadol suppository, intra-venous paracetamol and diclofenac suppository for post-caesarean pain relief, side effects, time of starting breastfeeding, uterine retraction, vaginal bleeding, the time between caesarean section and ambulation and duration of first rescue analgesic requirement among the three groups. Material and Methods: A randomized controlled prospective study was done over 90 postpartum women who underwent caesarean section under spinal anaesthesia. Randomization was done using a computer-generated random number table (before caesarean section) in groups A, B, and C; each group consisted of 30 pregnant women. Group A- The patient received a tramadol suppository of 100 mg per rectally within 30 minutes of skin closure after caesarean section. Group B- patient received a paracetamol injection of 1 gm in 100 ml normal saline by intravenous route over 15 minutes within 30 minutes of skin closure after caesarean section, and group C- patient was given diclofenac suppository 100 mg per rectally within 30 minutes of skin closure after caesarean section. All patients of group A and group C received paracetamol infusion 1 gm in 100 ml normal saline routinely within 30 minutes of caesarean section. Pain was assessed using Visual Analogue Scale at 1, 2, 3, 4, 6, 8, 10, 12 and 24 hours after caesarean section. Results: VAS score was found to be least in Diclofenac suppository with paracetamol infusion followed by combination analgesia of tramadol suppository plus paracetamol infusion and monotherapy of paracetamol infusion alone. In group A, B and C; 20%, 70% and 6.7% of subjects required rescue analgesia respectively. Out of all subjects among all three groups, 33.3 % of subjects from Group A, 23.3 % from Group B, and 6.7 % of subjects from Group C had adverse effects, with a p-value of 0.038. Conclusion: It can be concluded from the results that combination analgesia of Diclofenac suppository with paracetamol infusion is a better preventive analgesic than combination analgesia of tramadol suppository plus paracetamol infusion and monotherapy of paracetamol infusion alone with a lesser number of subjects requiring rescue analgesia.