Background: Hypertension is a prevalent chronic condition requiring consistent medication adherence to prevent complications. Non-adherence remains a significant barrier to effective blood pressure control. Mobile health (mHealth) applications have emerged as potential tools to enhance adherence through reminders, tracking, and real-time engagement. This study evaluates the impact of mHealth applications on medication adherence among hypertensive patients across multiple outpatient specialty clinics. Materials and Methods:A prospective, observational study was conducted over 6 months in three multi-specialty outpatient departments, including cardiology, general medicine, and internal medicine. A total of 200 hypertensive patients aged 30–70 years were recruited and divided into two groups: intervention group (n=100) using a standardized mHealth app with medication reminders and tracking features, and control group (n=100) receiving routine care. Medication adherence was assessed using the Morisky Medication Adherence Scale (MMAS-8) at baseline, 3 months, and 6 months. Blood pressure readings were also recorded during each visit. Results:At baseline, the mean MMAS-8 score was 4.2 ± 1.1 in both groups. After 6 months, the intervention group showed a significant increase in adherence scores (mean MMAS-8: 7.1 ± 0.8) compared to the control group (mean MMAS-8: 5.0 ± 1.2; p< 0.001). Additionally, 78% of patients in the intervention group achieved target blood pressure levels (<140/90 mmHg), versus 54% in the control group. Patient satisfaction with mHealth usage was reported as high in 85% of users. Conclusion:The use of mobile health applications significantly improves medication adherence and blood pressure control in hypertensive patients. Integration of mHealth tools in outpatient care models may enhance long-term disease management and patient outcomes.