Original Articles
A prospective comparative study of intravenous bolus norepinephrine and phenylephrine in maintaining arterial blood pressure during spinal anaesthesia in caesarean section | |
Dr. Praveen Thangavel, Dr. Shivaleela.H,Dr. Sureshbabu G.H.Dr. Komala B | |
Maternal hypotension is the most common complication after spinal anaesthesia during cesarean delivery, therefore preventing hypotension reduces the incidences of intraoperative nausea and vomiting other effects like dizziness and decreased consciousness. It also leads to hypoxia and acidosis in fetus. A vasopressor is usually required due to the poor efficacy of non-pharmacological techniques. Primary aim of this study is to compare the efficacy of Intermittent Intravenous bolus Norepinephrine and Phenylephrine in maintaining arterial blood pressure during spinal anaesthesia in caesarean section. A prospective comparative study conducted in the Department of Anesthesiology, in 102 Pregnant women belonging to the age group of 18-40 years posted for either elective/emergency caesarean surgeries under subarachnoid block accepted under ASA 2, satisfying the inclusion criteria and willing to participate in the study. The selected patients were randomly allocated into 2 groups containing 51 patients each according to the study drug; Norepinephrine group (4μg/ml) (Group N) and Phenylephrine group (100µg/ml) (Group P). Both the drugs maintained the systolic blood pressure following spinal anaesthesia throughout the surgery. In group N, not a single patient developed bradycardia, whereas in group P, bradycardia was observed in 7 patients (p=0.018).We conclude that the study of intravenous bolus norepinephrine and phenylephrine in maintaining arterial blood pressure during spinal anesthesia in cesarean section, both drugs effectively counteracted hypotension. |
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